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Vol. 1 No. 4 (2010): October-December 2010

Conventional as well as Microwave Assisted Synthesis Characterization and Antimicrobial Studies of Some New Derivatives of -5-[2'-Marcapto-1-Methylene)-(1', 3’, 4’-Thiadiazoles)] - 1, 2, 3-Benzotriazoles

DOI
https://doi.org/10.37285/ijddd.1.4.2
Submitted
November 25, 2024
Published
2024-11-28

Abstract

As a part of systematic investigation of conventional as well as microwave assisted synthesis and antimicrobial activity, of several new 5-[(2'-N-sub.arylidene hydrazinothioacetyl)-1-(methylene)-1',3',4'-thiadia-zoles)]-1,2,3-benzotriazoles 3a and 5-[(2'-sub.aryl-3'"-chloro-2'"-oxo-azetidine)-1"-(iminothioacetyl)-1-(methylene-1',3',4'-thiadiazole)]-1,2,3-benzotriazole1 as the starting material. All the synthesized products were evaluated for their antibacterial activity against Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae and Bacillus substilis and antifungal activity against Aspergillus Niger, Aspergillus flavus, Fusarium oxisporum and Trichoderma viride. The structures of all the synthesized compounds have been determined by spectral and chemical methods.

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