Articles

Vol. 2 No. 2 (2011): April – June 2011

Microwave-Assisted Synthesis and Antimicrobial Activity of Novel Azetidinones from Dehydroacetic Acid

Chetan P. Pulate^▸^▾
Gurubasavrajswamy P. M.^▸^▾
Rishikesh V Antre^▸^▾
Divakar Goli^▸^▾

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DOI: https://doi.org/10.37285/ijddd.2.2.7
Submitted: November 28, 2024
Published: 2024-12-08

Abstract

This paper describes the reaction of dehydroacetic acid with primary aromatic amines to yield Schiff bases (2a-2g) by using microwave system. Schiff bases irradiated with dimethyl formamide in presence of triethyl amine and chloroacetyl chloride to afford azetidinones (3a-3g) in excellent yields. The products, characterized on the basis of spectral data, have shown moderate to good antimicrobial activity against some bacteria and fungi.

References

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Keywords

Dehydroacetic acid
2-Azetidinones
Antimicrobial

How to Cite

Pulate, C. P., P. M., G., Antre, R. V., & Goli, D. (2024). Microwave-Assisted Synthesis and Antimicrobial Activity of Novel Azetidinones from Dehydroacetic Acid . International Journal of Drug Design and Discovery, 2(2), 483–487. https://doi.org/10.37285/ijddd.2.2.7

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