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Articles

Vol. 1 No. 3 (2010): July–September 2010

New Thiazolidinyl Quinazolinones and their Microbial Activity Studies

DOI
https://doi.org/10.37285/ijddd.1.3.5
Submitted
November 24, 2024
Published
2010-08-15

Abstract

A series of Schiff base 3-14 and 4-thiazolidinone 15-26 have been prepared. New compounds have been examined on the basis of elemental analysis, IR, 1H NMR and 13C NMR spectra. Minimum Inhibitory Concentrations (MIC) of new compounds viz antibacterial activity against four different strain viz two Gram positive and two Gram negative bacteria and antifungal activity against three fungal species have been studied and compared with standard drugs.

References

  1. [1] Ahmed, M.; Sharma, R.; Nagda, D.P.; Jat, J.L.; Talesara,
  2. G. L. ARKIVOC 2006, xi, 66.
  3. [2] Al-Rashood, S.T.; Aboldahab, I.A.; Nagi, M.N.; Abouzeid, L.A.; Alaa, A.M.; Abdel-hamide, S.G.; Youssef, K.M.; Al-Obaid, A.M.; El-Subbagh, H.I. Bioorg. & Med. Chem. 2006, 14, 8608.
  4. [3] El-Hellby, A.G.A.; Wahab, M.H.A. Acta Pharm. 2003, 53, 127.
  5. [4] Kumar, A.; Rajpu, C.S.; Bhati, Kumar, S. Bioorg. & Med. Chem. 2007, 15, 3089.
  6. [5] Saleh, M.A.; Abdel-Megged, M.F.; Abdo, M.A.; Abdel-Basset, S.M. Nucleosides, Nucleotides & Nucleic Acids 2002, 21(1), 93.
  7. [6] Barreca, M.L.; Balzarini, J.; Chimirri, A.; Clercq, E.D.; Luca, L.D.; Holtje, H.D.; Holtje, M.; Monforte, A.M.; Monforte, P.; Pannecouque, C.; Rao, A.; Zappala, M. J. Med. Chem. 2002, 45, 5410.
  8. [7] Liu, H.; Li, Z.; Anthonsen, T. Molecules 2000, 5, 1055.
  9. [8] Mosaad, S.M.; Mohammed, K.I.; Ahmed, M.A.; Abdel-Hamide, S.G. J. Applied Sci. 2004, 4(2), 302.
  10. [9] Sayyed, M.; Mokle, S.; Bokhare, M.; Mankar, A.; Surwase, S.; Bhusare, S.; Vibhutea, Y. ARKIVOC 2006, ii, 187.
  11. [10] Patel, N.B.; Lilakar, J.D. Ind. J. Heter. Chem. 2001, 11, 86.
  12. [11] Patel, N.B.; Chaudhari, R.C. J. Ind. Chem. Soc. 2006, 83, 838.
  13. [12] Patel, N.B.; Patel, V.N. Iranian J. Pharm. Res. 2007, 6(4), 251.
  14. [13] Patel, N.B.; Patel, J.C. J. Saudi Chem. Soc. 2008, 12(1), 121.
  15. [14] Patel, N.B.; Patel, V.N. Ind. J. Heter. Chem. 2007, 16, 247.
  16. [15] Ahluwalia, V. K.; Aggarwal, R. In Comprehensive Practical Organic Chemistry; Universities Press (India) limited, 2000; pp 69.
  17. [16] Myers, A.G.; Zheng, B.; Movassaghi, M. J. Org. Chem. 1997, 62, 7507.
  18. [17] Rattan A., In Antimicrobials in laboratory medicine, Churchill B I, Livingstone, New Delhi, 2000; pp 85.

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